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Top Python Libraries for Desktop Apps Only

Top Python Libraries for Desktop Apps Only

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if your focus is solely on building desktop apps, here are the best Python GUI libraries for desktop application development, ranked by suitability, stability, look-and-feel, and support

Category: Blog
Added On: June 28, 2025
Developer: By Praveen

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Top Python Libraries for Desktop Applications

Library Best For Platform License Look & Feel
PyQt / PySide Professional-grade apps Win / macOS / Linux GPL / LGPL Native / Modern
wxPython Native-looking apps Win / macOS / Linux Free (wxWidgets) Native
Tkinter Simple scripting GUIs Win / macOS / Linux Built-in Basic
Dear PyGui Tools, dashboards Win / macOS / Linux MIT Custom GPU UI
Kivy Touch/multitouch UI Win / macOS / Linux MIT Custom
GTK (PyGObject) Linux-native apps Linux / some Win/macOS LGPL Modern (GNOME)


Example Code & Links


✅ 1. PyQt / PySide

  • Best For: Professional-grade apps with complex layouts.

  • Pros: Tons of widgets, themes, drag-and-drop UI design via Qt Designer.

  • Cons: PyQt is GPL/commercial; PySide is LGPL (safer for closed source).

from PyQt5.QtWidgets import QApplication, QLabel
app = QApplication([])
label = QLabel('Hello, PyQt!')
label.show()
app.exec()

Official PyQt/PySide Website 


✅ 2. wxPython

  • Best For: Native-looking apps with cross-platform support.

  • Pros: Clean UI, strong Windows support.

  • Cons: Heavier, less community support than PyQt.

import wx
app = wx.App()
frame = wx.Frame(None, title=\"Hello wxPython\")
frame.Show()
app.MainLoop()

Official wxPython Website



✅ 3. Tkinter

  • Best For: Lightweight tools, learning, rapid prototyping.

  • Pros: Comes with Python, no install.

  • Cons: Old-school look (unless themed with CustomTkinter).

import tkinter as tk
root = tk.Tk()
tk.Label(root, text=\"Hello Tkinter\").pack()
root.mainloop()

Tkinter Documentation



✅ 4. Dear PyGui

  • Best For: Tools, dashboards, debug utilities.

  • Pros: GPU-rendered, very fast, immediate-mode GUI.

  • Cons: Not for traditional form-based apps.

from dearpygui import dearpygui as dpg
dpg.create_context()
dpg.create_viewport(title='Hello DPG')
dpg.add_text(\"Hello from Dear PyGui\")
dpg.setup_dearpygui()
dpg.show_viewport()
dpg.start_dearpygui()
dpg.destroy_context()

Dear PyGui Docs



✅ 5. Kivy

  • Best For: Multitouch, mobile-like interfaces on desktop.

  • Pros: Highly customizable; supports mobile too.

  • Cons: Doesn't use native OS controls.

from kivy.app import App
from kivy.uix.label import Label
class MyApp(App):
    def build(self):
        return Label(text='Hello Kivy')
MyApp().run()

Kivy Official Site



✅ 6. GTK (via PyGObject)

  • Best For: Linux-focused GUI applications.

  • Pros: Modern look in GNOME/Linux.

  • Cons: Less ideal for Windows/macOS.

import gi
gi.require_version('Gtk', '3.0')
from gi.repository import Gtk
win = Gtk.Window(title='Hi')
win.connect('destroy', Gtk.main_quit)
win.show_all()
Gtk.main()

GTK via PyGObject Docs